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Arterra Pet Science Clinical Study
New Science
May 02, 2024

Arterra Pet Science Clinical Study

Help Shape the Future of Canine Wellness with Arterra Pet Science.

At Arterra Pet Science, we're committed to providing the most comprehensive, all-in-one daily dog supplement to ensure a healthier, longer life for our canine companions. Our ongoing dedication to excellence and innovation in pet health is why we're excited to announce our new...

Arterra Pet Science Clinical Study

Arterra Pet Science Clinical Study

Help Shape the Future of Canine Wellness with Arterra Pet Science. At Arterra Pet Science, we're committed to providing the most comprehensive, all-in-one daily dog supplement to ensure a healthier, longer life for our canine companions. Our ongoing dedication to excellence and innovation in pet health is why we're excited to announce our new clinical study exclusively for senior dogs aged 8 years and older, based in Austin. Why Participate? This study is an essential step in further validating the impressive clinical results our supplements have shown and offering new insights into the wellness advancements Arterra delivers. By participating, you will not only contribute to the science that helps all dogs live better lives but also receive exclusive benefits: Free Three-Month Supply of Arterra’s Senior Dog Supplement. Complimentary Lab Work including two blood tests. Expert Veterinary Care with two free vet visits throughout the study. Zero Cost — The study is 100% funded by Arterra, ensuring no expenses for you. Assured Safety for Your Beloved Pet We prioritize your dog's health and safety above all. Every ingredient in our supplement has been vet-formulated, science-backed and quality-tested, ensuring the Arterra supplement is 100% safe for your pet. Study Overview Phase 1: Baseline Assessment — We document your dog's current weight, health status, dietary habits, and any medications or supplements.Phase 2: Treatment Period — Initiation of the Arterra supplement tailored to your dog’s weight, along with regular monitoring and veterinary assessments.Phase 3: Post-Treatment Evaluation — A final evaluation to compare health outcomes from start to finish, ensuring a comprehensive understanding of the supplement’s effects. Your Role in Advancing Dog Health As a participant, you’ll be asked to maintain a simple daily log of your dog’s behavior, appetite, and overall well-being, alongside scheduled vet visits for health assessments and blood work. This detailed monitoring helps us ensure the highest impact of our supplement. Sign Up Today! If you're an Austin-based dog owner with a senior pet, we invite you to join this groundbreaking study. Your participation will be instrumental in enhancing canine health innovations and could potentially add joyful, active years to your dog's life. Spaces are limited, so don't miss this opportunity to be part of something that can significantly improve canine health standards. For more information and to register your interest, please contact our PAZ Veterinary Arterra study coordinator directly at (512) 236-8000 or email us at support@arterrapet.com. Let's work together to make a lasting impact on the well-being of our beloved pets!

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Arterra vs. Leap Years - An In-Depth Comparison

Arterra vs. Leap Years - An In-Depth Comparison

2024 is poised for an explosion of consumer and investor interest in the burgeoning canine longevity space. I believe that Arterra, together with two other companies, Loyal and Leap Years, currently represent the three most compelling approaches to extend and enhance canine lifespan. As a passionate dog lover and advocate for healthier canine aging, I’m first and foremost excited that, for the first time, our space has three quality companies pursuing distinct paths in support of this mission, and that all of us – in my humble opinion – are doing good work. Last month I addressed in detail how Arterra’s whole-body approach to canine wellness compares and contrasts to Loyal’s pharmaceutical path. Today, I’d like to deep dive into how our products compare to Leap Years’. Leap Year’s Approach Leap Year’s products are comprised of just two active ingredients, LY-D2, an NAD+ precursor, and LY-D6, a flavonoid compound that acts as a senolytic agent. Because their ingredients are patented, we don’t have full transparency into exactly what they are, but their patent application gives several clues. Without going down a very deep rabbit hole that I suspect would make most readers’ eyes glaze over, let’s accept their own high-level summary of their two compounds. Their approach is twofold: Boost NAD+ levels to increase cellular energy production, which drives a downstream host of benefits in areas such as cognition, energy/vitality, cardiovascular health, and regulating inflammation. Support the clearance of senescent (old and dysfunctional) cells via a senolytic flavonoid compound. These are two powerful strategies that I would expect to produce a range of healthspan-promoting benefits. To Leap Years’ strong credit, they’ve nearly finished validating these benefits with a clinical study due this spring (Arterra’s will follow a few months behind, this fall). My review, in short, is that they have an excellent product that likely works as advertised. But I also believe that it’s very expensive for what it is, and that Arterra’s products represent not only a superior and more comprehensive approach to healthy canine aging, but also a better value for the money. I’ll explain why. Arterra’s Approach As a starting point, I think it’s important to establish that our formulas — similarly to Leap Years — also contain senolytic polyphenols and flavanoids (notably quercetin, resveratrol, trans-pterostilbene, turmeric, and green tea-derived catechins). Further, assuming a dog is consuming a nutritionally complete diet with adequate sources of Vitamin B3 and the amino acid tryptophan, our flavanoids also support the conversion of these precursor molecules into metabolically active NAD+. So in a meaningful way, both Arterra and Leap Years provide overlapping benefits for these two dimensions of aging. With this said, our approach to healthy aging is much broader and more aggressive than theirs. We believe that the body is an astonishingly complex system, and that modern science has not yet discovered any one or two “silver bullets” capable of supporting healthy aging alone. But what we do have is a pharmacopeia of dozens of well-studied, naturally occurring molecules that individually help chip away at the problem of aging through multiple strategies, vectors, and pathways, and which together produce an entourage effect greater than the sum of their parts.  To this end, Arterra’s flagship Adult and Senior formulas are comprised of 46 and 63 science-backed ingredients spanning eight functional domains, each supported through multiple pathways. These are:   Longevity – Focused on epigenetic activation of the SIRT1 and AMPK pathways, mitochondrial health, reducing formation of advanced glycation end products (AGEs), and senolytic agents to help the body clear senescent cells. Check out our blog posts for deeper dives into these topics. Joint Support and Comfort – Supporting the underlying structural health of the joints through high doses of collagen, including bone broth-derived Type II Collagen, by promoting hydration within the joints, reducing inflammation, supporting tendon and ligament strength and recovery, and reducing discomfort from age-related degeneration of cartilage. Cognition and Mood – Supporting in parallel the underlying health of the brain by increasing BDNF, NGF, synaptic density, and circulation, while increasing the availability of neurotransmitters involved in positive mood, energy, and motivation. Organ Support – Supporting the healthy function of the liver, heart, and vascular system. Immune support – A multi-pronged approach to a healthy immune system, with target benefits ranging from relief of occasional seasonal allergies to preventative support for more serious immune-related conditions. Gut Health – Formulated first to improve the integrity of the gut and intestinal lining (aka “leaky gut” support – a widespread issue for dogs fed a standard American kibble diet), with additional pre- and pro-biotic support for a healthy microbiome. Healthy Stress Response – A potent blend of adaptogenic herbs and mushrooms to help the body cope with environmental and physical stress through increased stamina and recovery, and decreased production of cortisol (a damaging stress hormone when overexpressed). Antioxidant Support – To reduce oxidative stress in synergistic harmony with the rest of our formula. For a deeper dive into our complete formula, check out the Ingredient Explorer on our product page. Any one of these systems can be a critical point of failure for a dog’s longevity or quality of life, which is why we’ve carefully designed our formula to support all of them in harmony. We’ve further formulated with a philosophical eye toward what I like to call “hardware,” and “software” support, with the former class of ingredients supporting the structures, building blocks, and resilience of a given system, and the latter supporting its metabolic programming via epigenetic modulation, cell metabolism, and other factors. Together, I believe Arterra’s approach represents the most comprehensive, powerful, and efficacious canine supplement ever brought to market. Arterra vs. Leap Years Let’s first bump the two overlapping areas of our formula head-to-head – as a senolytic, and as an NAD+ booster. Based on the information that can be gleaned from Leap Years’ patent, as a senolytic stack I would expect the performance of our formula to be roughly in line with theirs. In good faith, I would call this measure a tie. However, as an NAD+ booster, specifically, their product is almost certainly superior, though ours does still provide notable coverage here. So on this one metric, they win. But I believe strongly that Leap Years’ one likely advantage in NAD+ promotion is vastly offset and surpassed by our multi-pronged approach to whole-body anti-aging. In fact, we looked heavily at this exact question when developing our formula with our veterinary partners. We carefully explored including NAD+ precursors such as NMN, NR, or NADH, but found that the cost of including this one great ingredient was so expensive that we could literally include 20 other very good ones for the same price. When confronted with this tradeoff, I made the mission-driven decision to take this deal and opt for breadth. And given the unparalleled scope of benefit coverage this tradeoff empowered – unmatched by Leap Years or any other competitor – I maintain that it was a good one. Finally, a fair comparison of our two products must consider price. Both Arterra and Leap Years’ products are expensive relative to legacy pet supplement brands, and necessarily so due to the cost of our premium ingredients. Leap Years’ pricing ranges from $31/month for small dogs to $117/month for extra-large breeds. This puts their pricing roughly in line with our 46-ingredient Adult Formula (which can also be given to seniors), which starts at $25/month for small dogs and rises to $99 for large breeds. Given Arterra’s vastly broader range of functional benefits over Leap Years’, and considering the overlapping coverage of broad senolytic support between the two products, as well as Arterra’s (admittedly weaker, but still noteworthy) NAD+ support, I believe our Adult Formula represents a dramatically superior value for the money – one that I strongly expect will drive more powerful and observable improvements in quality of life. Taking the comparison a step further, Arterra’s more expensive flagship 63-ingredient Senior Formula dials up the volume on everything in our preventative Adult Formula, while adding an additional class of ingredients focused specifically on quality-of-life improvements for older dogs already experiencing the consequences of degenerative aging. These ingredients were selected to help your older dog feel more comfortable in their aging body and mind. I am deeply proud of this product, and believe that — beyond a quality diet —it is today the single most powerful intervention for healthy canine aging available on the market at any price. Our Senior Formula is, however, quite expensive, ranging from $50/month for small dogs up to $160/month for large breeds. In this regard it is indeed a modst step up in price from Leap Years’ product, but also in breadth and, I believe, efficacy. Our confidence in the ability of both Arterra formulas to drive obvious results is so strong that we back them with a 100% moneyback guarantee. If you can’t see a positive change in your dog within 30 days, we’ll refund your purchase price without hassle. This is notably a guarantee that Leap Years does not offer. And since our launch three months ago, less than 2% of our customers have taken us up on it, which tells us (and hopefully you too) a lot about the performance of what we’ve created. In summary, I believe that Leap Years has launched an excellent product, but that our Adult Formula is a better and more effective value for the money. And for those wanting to max out what’s possible within the natural pharmacopeia for their older dogs, our Senior Formula offers an even more powerful solution that’s unrivaled on the market at any price. Our clinical study is underway and won’t be completed until this fall, so until the results are published I’ll have to ask you to take my word on good faith. But I hope that for the interim, I’ve done a thorough and fair job of substantiating why I believe this to be the case. I respect Leap Years and believe their team is smart, thoughtful, and sincere. I also believe the market for healthy canine aging is in its infancy and poised for explosive growth, and that there’s plenty of room for both brands to thrive commercially while delivering on our missions. And so it’s in the spirit of transparency, consumer education, and healthy competition that I’ve made this comparison between our products. If anyone in the community believes I’ve been unfair in my analysis, inaccurate in my science, or otherwise missed something important, don’t hesitate to reach me directly at jonathan@arterrapet.com.   Jonathan Willbanks Founder & CEO Arterra Pet Science

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Arterra vs. Loyal – Comparing Two Paths to Canine Longevity

Arterra vs. Loyal – Comparing Two Paths to Canine Longevity

After nearly two years of behind the scenes work, we launched Arterra last month – the first canine supplement specifically designed to increase canine healthspan. Earlier this week, pharmaceutical startup Loyal announced their plans to begin an FDA trial for a drug designed to increase lifespan in large dogs. Given the strong overlap between our companies’ missions, my inbox was quickly flooded with inquiries about how our product compares to theirs. So I thought I’d write a post sharing my thoughts on the important similarities and differences between Arterra and Loyal’s approach.

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Unleash Your Dog's Inner Genius: How Arterra Pet Science Boosts Canine Cognition and Mood

Unleash Your Dog's Inner Genius: How Arterra Pet Science Boosts Canine Cognition and Mood

Just like humans, dogs can suffer cognitive decline, depression, and dementia in their old age. For owners of senior dogs, watching your friend’s mental faculties, energy, and mood start to fade away can be one of the hardest parts of their golden years, and among the most detrimental to their quality of life.  

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Why Our Products are Expensive

Why Our Products are Expensive

Arterra is the most advanced pet supplement ever brought to market. This isn’t marketing hype. It is factually true by an order of magnitude, and we will happily invite side-by-side comparisons with any competitor aiming to challenge this claim. It is also, as a consequence, the most expensive. Rather than try to whistle around this fact, I intend to explain directly why our products are expensive, and to articulate why, despite our price point, we offer the best value and efficacy of anything on the market.

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The Power of Natural Ingredients for Canine Joint Health

The Power of Natural Ingredients for Canine Joint Health

As pet owners, we all want to ensure that our furry companions enjoy a happy, active, and comfortable life. While aging-related joint discomfort is common in dogs, there are natural ways to support their joint health and overall well-being. In this article, we'll explore the benefits of various ingredients commonly found in canine joint support supplements.  Why Joint Health Matters for Dogs Before diving into the specific ingredients, it's essential to understand why joint health is crucial for our canine friends. Dogs, like humans, rely on their joints for mobility, flexibility, and an active lifestyle. Over time, wear and tear on these joints can lead to reduced joint comfort and mobility. This is where natural joint support ingredients come into play, helping dogs maintain their zest for life. 1. Beef Bone Broth Concentrate Beef bone broth concentrate is a natural source of collagen, glucosamine, and chondroitin. Collagen provides the structural framework for joints and bones, while glucosamine and chondroitin promote joint lubrication and flexibility. Beef bone broth concentrate is a delicious and easily digestible way to support joint health in dogs. 2. Hydrolyzed Bovine Collagen Peptides Hydrolyzed bovine collagen peptides are a bioavailable source of collagen. Collagen is a vital component of connective tissues, making it essential for joint health. By providing dogs with this easily absorbed form of collagen, you can help maintain joint strength and flexibility. 3. Reishi Mushroom (Fruiting Body) and Shiitake Mushroom (Fruiting Body) Reishi and shiitake mushrooms have been used in traditional medicine for their potential health benefits. They contain bioactive compounds that may help support a healthy inflammatory response, a common contributor to joint issues. Incorporating these mushrooms into your dog's diet can support overall well-being and joint comfort. 4. Chondroitin Sulfate (Bovine) and Glucosamine Sulfate (Bovine) Chondroitin sulfate and glucosamine sulfate are well-known joint health supplements. Chondroitin helps maintain joint cartilage, while glucosamine supports joint cushioning and lubrication. These bovine-derived ingredients are often used together to provide comprehensive joint support for dogs. 5.MSM (Methylsulfonylmethane) Methylsulfonylmethane (MSM) is a naturally occurring compound that contains sulfur, a crucial element for healthy joints. MSM support a healthy inflammatory response and promotes joint comfort. Integrating MSM into your dog's diet can aid in their overall joint health. 6. Boswellia Serrata Extract Boswellia serrata extract is derived from the resin of the Boswellia tree. It is a natural COX-2 inhibitor with anti-inflammatory properties that can benefit dogs experiencing joint discomfort. By reducing inflammation, this natural extract may contribute to improved joint comfort and mobility 7. Turmeric Extract (Std. 95% Curcumin) Turmeric extract, standardized to contain at least 95% curcumin, is a well-known anti-inflammatory agent. Curcumin's powerful anti-inflammatory and antioxidant properties make it an excellent choice for supporting joint health in dogs. It can help manage discomfort and enhance overall well-being. 8. Tart Cherry Extract Tart cherry extract is rich in antioxidants and contains compounds that may help reduce inflammation. It has been studied for its potential benefits in managing joint discomfort. Including tart cherry extract in your dog's joint support regimen may contribute to their joint health and comfort. 9. Sodium Hyaluronate (Hyaluronic Acid) Sodium hyaluronate, also known as hyaluronic acid, is a key component of joint fluid and cartilage. It plays a vital role in maintaining joint lubrication and cushioning. By supplementing your dog's diet with hyaluronic acid, you can support their joint mobility and overall joint comfort. Choosing the Right Joint Support for Your Dog When selecting a joint support supplement for your dog, it's essential to consider their unique needs and consult with your veterinarian. Factors such as breed, age, and activity level can influence the choice of ingredients and dosage. Natural ingredients like beef bone broth concentrate, hydrolyzed bovine collagen peptides, mushrooms, chondroitin sulfate, glucosamine sulfate, MSM, Boswellia serrata extract, turmeric extract, tart cherry extract, and hyaluronic acid can be valuable additions to your dog's joint health regimen. These ingredients work synergistically to promote joint comfort and mobility, helping your furry friend enjoy a happier and more active life. All of these are included in Arterra’s Senior Formula, along with 52 other ingredients to support full-body health, mood, and longevity. Most of them are also included in our Adult Formula. No other supplement offers the breadth, quality, and potency of our all-in-one daily formula.

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